DETRONIN TABLET & SYRUP

Description

PROPERTIES:
DETRONIN (oxybutynin chloride), in the form of syrup and tablets, has high efficacy in the treatment of the manifestations of overactive bladder in adults and children. DETRONIN exerts direct antispasmodic and antimuscarinic effects on smooth muscles. Its antimuscarinic effect is less than that of atropine but its antispasmodic activity is 4 – 10 times greater than that of atropine on the detrusor muscle. DETRONIN relaxes bladder smooth muscle, increases bladder capacity, diminishes the frequency of uninhibited contractions of the detrusor muscle and delays the initial desire to void in patients with involuntary bladder contractions. It has no antinicotinic effects and is well tolerated.
INDICATIONS:
DETRONIN (syrup and tablets) is indicated in cases of overactive bladder to relieve the symptoms of:
– Urinary urgency.
– Increased frequency of micturition.
– Urge incontinence.
– Nocturnal enuresis.
DOSAGE:
Adults:1 tablet or 1 teaspoonful 2 – 3 times daily or as directed by the physician.
Children:1 tablet or 1 teaspoonful 2 times daily or as directed by the physician.
SIDE EFFECTS:
DETRONIN is safe and well tolerated. Mild side effects such as dry mouth, decreased sweating, constipation, drowsiness or blurred vision may occur.
CONTRAINDICATIONS:
Hypersensitivity to oxybutynin chloride. As with other anticholinergic drugs, the drug is contraindicated in patients with narrow angle glaucoma, intestinal obstruction, obstructive uropathy, pregnancy, and children below 12 kg.
DRUG INTERACTIONS:
Alcohol and sedatives enhance drowsiness that may occur in some patients.
PRECAUTIONS:
As with other anticholinergics, caution is required while driving cars or operating dangerous machinery and in patients with enlarged prostate.

PACKING:
A box containing 20 tablets.
A bottle containing 60, 100 or 120 ml syrup.

STORAGE:
Keep at a temperature (15 – 30 °C). Keep out of reach of children.