Description
Pharmacological action:
MENTOPROFEN gel contains ketoprofen, a nonsteroidal anti-inflammatory drug, which inhibits prostaglandin synthesis through inhibition of cyclo-oxygenase enzyme, thus resulting into pronounced analgesic and anti-inflammatory properties. Camphor is a counter-irritant, rubefacient and mild analgesic, thus, it is useful in fibrositis, neuralgia and similar conditions. The inclusion of menthol and alcohol in mentoprofen gel adds to the counter-irritant and analgesic actions. Alcohol also acts as a penetration enhancer resulting into rapid onset of action and improved activity. Mentoprofen gel is beneficial in many rheumatic and inflammatory disorders of musculoskeletal structures.
pHarmacokinetics:
Ketoprofen is slowly absorbed through the skin when locally applicated in form of gel.
INDICATIONS:
Acute painful musculoskeletal conditions caused by trauma such as sports injuries, sprains, strains and contusions.
Musculoskeletal rheumatic and inflammatory disorders involving muscles, tendons, ligaments and joints.
DOSAGE & ADMINISTRATION:
Apply mentoprofen gel on the skin with gentle rubbing 2 – 4 times daily.
CONTRAINDICATIONS:
Hypersensitivity to any of the components.
SIDE EFFECTS:
Mentoprofen gel is well-tolerated. Rare cases of local skin reactions may occur.
DRUG INTERACTIONS:
The drug interaction of ketoprofen after normal application as gel has low probability as the systemic diffusion is very weak.
PREGNANCY & LACTATION:
Avoid using it during pregnancy or breast feeding.
PRECAUTIONS & warnings:
• Contact with eyes, mucous membranes or broken skin should be avoided.
• Avoid using the gel more than 12 days.
• Protect the treated area from direct sunlight exposure during treatment and for 2 weeks after treatment period.
• Skin adverse reactions may occur when topical ketoprofen is used together with octocrylene.
• Stop using the gel if any skin sensitization occur.
PACKING:
A tube containing 20 g.
STORAGE:
Keep at a temperature not exceeding 30C, in dry place.
Keep out of reach of children.
INSTRUCTIONS TO PATIENTS:
• Hands should be washed immediately after use.
• Avoid excessive exposure to sunlight of area treated in order to avoid possibility of photosensitivity.
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